Thyquidity

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USE

THYQUIDITY® (levothyroxine sodium) oral solution is a prescription medicine that contains a hormone called levothyroxine that is normally produced in your body by the thyroid gland. THYQUIDITY is used:

to replace or give extra levothyroxine in people whose thyroid gland does not naturally produce enough (a condition called hypothyroidism); or
with surgery and radioiodine therapy to manage a type of thyroid cancer called thyroid-dependent well-differentiated thyroid cancer.

THYQUIDITY should not be used to treat people who are recovering from swelling of the thyroid gland (thyroiditis) and whose bodies do not produce enough levothyroxine for a short time.

IMPORTANT SAFETY INFORMATION

What is the most important information you should know about THYQUIDITY?

Do not use THYQUIDITY to treat weight problems or weight loss.
Do not take more THYQUIDITY than your doctor prescribes. Overdosage or taking too much THYQUIDITY may cause life-threatening side effects or death.

Do not take THYQUIDITY

if your adrenal glands are not working well and you have not been treated for this problem.

Before you take THYQUIDITY, tell your healthcare provider about all your medical conditions, including if you:

have or had heart problems
have or had thyroid nodules
have adrenal or pituitary gland problems
have any food or drug allergies
have a low red blood cell count (anemia)
have diabetes
have weak or weakening bones (osteoporosis)
have or had a history of blood clotting problems
have recently received radiation therapy with iodine (such as I-131)
are pregnant or plan to become pregnant. Your doctor may need to change your THYQUIDITY dose while you are pregnant.
are breastfeeding. THYQUIDITY can pass into breast milk. Talk to your doctor about the best way to feed your baby if you take THYQUIDITY.

Tell your doctor about all the medicines you take including prescription and over-the-counter medicines, vitamins, and herbal supplements. THYQUIDITY may affect the way other medicines work, and other medicines may affect how THYQUIDITY works. Ask your doctor or pharmacist for a list of medicines that may interact with THYQUIDITY.

What are the possible side effects of THYQUIDITY?

THYQUIDITY may cause serious side effects, including:

heart problems. You may experience increased heart rate, chest pain, and irregular heartbeat. Your risk of developing these problems may be greater if you are elderly, have heart problems, or if you take too much THYQUIDITY. Tell your doctor right away if you develop heart problems, as your doctor may choose to reduce your dose or stop treatment with THYQUIDITY.
worsening diabetic control. If you are diabetic, it may be harder to control your blood sugar levels causing hyperglycemia while taking THYQUIDITY. Check your blood sugar levels closely after starting, changing, or stopping treatment with THYQUIDITY. Your doctor may have to change your diabetes treatment plan.
weak or brittle bones. Your risk of developing weak or brittle bones may be greater if you are post-menopausal or if you take too much THYQUIDITY.

The most common side effects of THYQUIDITY include: fast or irregular heartbeat, chest pain, shortness of breath, leg cramps, headache, nervousness, irritability, sleep problems (insomnia), tremors, muscle weakness, change in appetite, weight loss, vomiting, diarrhea, sweating a lot, heat intolerance, fever, changes in menstrual period, and hives or skin rash.

Thyquidity contains glycerol, which can cause vomiting and diarrhea, which may result in serious dehydration in infants. Tell your doctor if you notice these symptoms in children up to 3 months old.

Partial hair loss may occur during the first months of treatment with THYQUIDITY. This is usually temporary, lasting a short period of time.

How should I take THYQUIDITY?

You should take THYQUIDITY exactly as your doctor tells you to take it.
Your doctor will tell you how much THYQUIDITY to take each day.
Your doctor may change your dose, if needed.
Take THYQUIDITY once each day, on an empty stomach, approximately 30 minutes to 1 hour before breakfast.
Certain medicines can interfere with how THYQUIDITY is absorbed by your body. Take THYQUIDITY:
- At least 4 hours before or after you take medicines or supplements that contain calcium or iron (calcium carbonate, ferrous sulfate, etc.); and
- at least 4 hours before you take medicines that contain bile acid sequestrants or ion exchange resins.
Know the medicines you take. Ask your doctor or pharmacist for a list of these medicines, if you are not sure.
Certain foods including soybean flour, cottonseed meal, walnuts, dietary fiber, and grapefruits or grapefruit juice may affect the way that your body absorbs THYQUIDITY. Talk to your doctor if you eat or drink these foods.
Your doctor should do certain blood tests while you are taking THYQUIDITY and may change your daily dose of THYQUIDITY as needed. Keep taking THYQUIDITY unless your doctor tells you to stop or change your dose.

USE ONLY AS DIRECTED BY YOUR HEALTHCARE PROFESSIONAL. These are not all the possible side effects of THYQUIDITY. Talk to your healthcare provider or pharmacist for more information or for medical advice about side effects.

You may report side effects to FDA at 1-800-FDA-1088 or by visiting www.fda.gov/medwatch.

Please see the full Prescribing Information, including BOXED WARNING.

All patient and physician images are representative only.

USE

to replace or give extra levothyroxine in people whose thyroid gland does not naturally produce enough (a condition called hypothyroidism); or
with surgery and radioiodine therapy to manage a type of thyroid cancer called thyroid-dependent well-differentiated thyroid cancer.

THYQUIDITY should not be used to treat people who are recovering from swelling of the thyroid gland (thyroiditis) and whose bodies do not produce enough levothyroxine for a short time.

IMPORTANT SAFETY INFORMATION

What is the most important information you should know about THYQUIDITY?

Do not use THYQUIDITY to treat weight problems or weight loss.
Do not take more THYQUIDITY than your doctor prescribes. Overdosage or taking too much THYQUIDITY may cause life-threatening side effects or death.

Do not take THYQUIDITY

if your adrenal glands are not working well and you have not been treated for this problem.

Before you take THYQUIDITY, tell your healthcare provider about all your medical conditions, including if you:

have or had heart problems
have or had thyroid nodules
have adrenal or pituitary gland problems
have any food or drug allergies
have a low red blood cell count (anemia)
have diabetes
have weak or weakening bones (osteoporosis)
have or had a history of blood clotting problems
have recently received radiation therapy with iodine (such as I-131)
are pregnant or plan to become pregnant. Your doctor may need to change your THYQUIDITY dose while you are pregnant.
are breastfeeding. THYQUIDITY can pass into breast milk. Talk to your doctor about the best way to feed your baby if you take THYQUIDITY.

What are the possible side effects of THYQUIDITY?

THYQUIDITY may cause serious side effects, including:

heart problems. You may experience increased heart rate, chest pain, and irregular heartbeat. Your risk of developing these problems may be greater if you are elderly, have heart problems, or if you take too much THYQUIDITY. Tell your doctor right away if you develop heart problems, as your doctor may choose to reduce your dose or stop treatment with THYQUIDITY.
worsening diabetic control. If you are diabetic, it may be harder to control your blood sugar levels causing hyperglycemia while taking THYQUIDITY. Check your blood sugar levels closely after starting, changing, or stopping treatment with THYQUIDITY. Your doctor may have to change your diabetes treatment plan.
weak or brittle bones. Your risk of developing weak or brittle bones may be greater if you are post-menopausal or if you take too much THYQUIDITY.

Thyquidity contains glycerol, which can cause vomiting and diarrhea, which may result in serious dehydration in infants. Tell your doctor if you notice these symptoms in children up to 3 months old.

Partial hair loss may occur during the first months of treatment with THYQUIDITY. This is usually temporary, lasting a short period of time.

How should I take THYQUIDITY?

You should take THYQUIDITY exactly as your doctor tells you to take it.
Your doctor will tell you how much THYQUIDITY to take each day.
Your doctor may change your dose, if needed.
Take THYQUIDITY once each day, on an empty stomach, approximately 30 minutes to 1 hour before breakfast.
Certain medicines can interfere with how THYQUIDITY is absorbed by your body. Take THYQUIDITY:
- At least 4 hours before or after you take medicines or supplements that contain calcium or iron (calcium carbonate, ferrous sulfate, etc.); and
- at least 4 hours before you take medicines that contain bile acid sequestrants or ion exchange resins.
Know the medicines you take. Ask your doctor or pharmacist for a list of these medicines, if you are not sure.
Certain foods including soybean flour, cottonseed meal, walnuts, dietary fiber, and grapefruits or grapefruit juice may affect the way that your body absorbs THYQUIDITY. Talk to your doctor if you eat or drink these foods.
Your doctor should do certain blood tests while you are taking THYQUIDITY and may change your daily dose of THYQUIDITY as needed. Keep taking THYQUIDITY unless your doctor tells you to stop or change your dose.

You may report side effects to FDA at 1-800-FDA-1088 or by visiting www.fda.gov/medwatch.

Please see the full Prescribing Information, including BOXED WARNING.

All patient and physician images are representative only.

USE

to replace or give extra levothyroxine in people whose thyroid gland does not naturally produce enough (a condition called hypothyroidism); or
with surgery and radioiodine therapy to manage a type of thyroid cancer called thyroid-dependent well-differentiated thyroid cancer.

THYQUIDITY should not be used to treat people who are recovering from swelling of the thyroid gland (thyroiditis) and whose bodies do not produce enough levothyroxine for a short time.

IMPORTANT SAFETY INFORMATION

What is the most important information you should know about THYQUIDITY?

Do not use THYQUIDITY to treat weight problems or weight loss.
Do not take more THYQUIDITY than your doctor prescribes. Overdosage or taking too much THYQUIDITY may cause life-threatening side effects or death.

Do not take THYQUIDITY

if your adrenal glands are not working well and you have not been treated for this problem.

Before you take THYQUIDITY, tell your healthcare provider about all your medical conditions, including if you:

have or had heart problems
have or had thyroid nodules
have adrenal or pituitary gland problems
have any food or drug allergies
have a low red blood cell count (anemia)
have diabetes
have weak or weakening bones (osteoporosis)
have or had a history of blood clotting problems
have recently received radiation therapy with iodine (such as I-131)
are pregnant or plan to become pregnant. Your doctor may need to change your THYQUIDITY dose while you are pregnant.
are breastfeeding. THYQUIDITY can pass into breast milk. Talk to your doctor about the best way to feed your baby if you take THYQUIDITY.

What are the possible side effects of THYQUIDITY?

THYQUIDITY may cause serious side effects, including:

heart problems. You may experience increased heart rate, chest pain, and irregular heartbeat. Your risk of developing these problems may be greater if you are elderly, have heart problems, or if you take too much THYQUIDITY. Tell your doctor right away if you develop heart problems, as your doctor may choose to reduce your dose or stop treatment with THYQUIDITY.
worsening diabetic control. If you are diabetic, it may be harder to control your blood sugar levels causing hyperglycemia while taking THYQUIDITY. Check your blood sugar levels closely after starting, changing, or stopping treatment with THYQUIDITY. Your doctor may have to change your diabetes treatment plan.
weak or brittle bones. Your risk of developing weak or brittle bones may be greater if you are post-menopausal or if you take too much THYQUIDITY.

Thyquidity contains glycerol, which can cause vomiting and diarrhea, which may result in serious dehydration in infants. Tell your doctor if you notice these symptoms in children up to 3 months old.

Partial hair loss may occur during the first months of treatment with THYQUIDITY. This is usually temporary, lasting a short period of time.

How should I take THYQUIDITY?

You should take THYQUIDITY exactly as your doctor tells you to take it.
Your doctor will tell you how much THYQUIDITY to take each day.
Your doctor may change your dose, if needed.
Take THYQUIDITY once each day, on an empty stomach, approximately 30 minutes to 1 hour before breakfast.
Certain medicines can interfere with how THYQUIDITY is absorbed by your body. Take THYQUIDITY:
- At least 4 hours before or after you take medicines or supplements that contain calcium or iron (calcium carbonate, ferrous sulfate, etc.); and
- at least 4 hours before you take medicines that contain bile acid sequestrants or ion exchange resins.
Know the medicines you take. Ask your doctor or pharmacist for a list of these medicines, if you are not sure.
Certain foods including soybean flour, cottonseed meal, walnuts, dietary fiber, and grapefruits or grapefruit juice may affect the way that your body absorbs THYQUIDITY. Talk to your doctor if you eat or drink these foods.
Your doctor should do certain blood tests while you are taking THYQUIDITY and may change your daily dose of THYQUIDITY as needed. Keep taking THYQUIDITY unless your doctor tells you to stop or change your dose.